• Bioinformatics for Agriculture, Health and the Environment
    A vital component of the African Genome Center, University Mohammed VI Polytechnic.
  • Computational Power
    Access to Africa's number 1 HPC cluster
  • By leveraging resourses
    We aim to centralize the bioinformatics needs and develop innovative research and training programs.

Our services

Acces website
CNN-MGP

Convolutional Neural Networks for Metagenomics Gene Prediction


Acces website
Contact Us

Please use the contact form to request any bioinformatics services, including genomics and proteomics data analysis, in silico pharmaceutical services, and research bioinformatics services. Services are offered for a fee or through collaboration.


Announcement

Postdoctoral Fellow in Bioinformatics

The bioinformatics laboratory of the African Genome Center at the University of Mohammed VI Polytechnic Benguerir Morocco is seeking applicants for a Postdoc Position in Bioinformatics/Computational Biology. The successful candidate will develop and maintain novel bioinformatics tools and algorithms. The candidate will work with an enthusiastic team of Ph.D. students and postdocs, with diverse backgrounds, including plant molecular biology, biomedical bioinformatics, machine learning, metagenomics as well as chemoinformatics.

The deadline: 2022-10-10


Our Publications

Acces journal
CicerSpTEdb: A web-based database for high-resolution genome-wide identification of transposable elements in Cicer species

In this publication, we present CicerSpTEdb, a comprehensive TE database for Cicer species that aims to improve our understanding of the organization and structural variations of the chickpea genome

Acces journal
A Network-Based Methodology to Identify Subnetwork Markers for Diagnosis and Prognosis of Colorectal Cancer

In this publication, we present a novel network-based method to detect subnetwork markers for patients with colorectal cancer (CRC).

Acces journal
PlantPathMarks (PPMdb): an interactive hub for pathways-based markers in plant genomes

This publication presents the PlantPathMarks database (PPMdb) as a comprehensive, web-based, user-friendly, and interactive hub for pathway-based markers in plant genomes

Acces journal
Developing a new genic SSR primer database in faba bean (Vicia faba L.)

The goal of this research was to develop a new genetic database of simple sequence repetition (SSR) primers for faba and classify them according to their target genes and respective biological processes

Acces journal
Machine learning applications in RNA modification sites prediction

In this publication, we comprehensively explore machine learning based approaches used for the prediction of 11 RNA modification types, namely, m1A, m6A, m5C, 5hmC, psi, 2OMe, ac4C, m7G, AtoI, m2G, and D

Acces journal
Genome-wide association analysis of chickpea germplasms differing for salinity tolerance based on DArTseq markers

This study used a chickpea population collected from ICARDA genebank. The germplasm included 186 genotypes with broad Asian and African origins and genotyped with 1856 DArTseq markers. Phenotyping for salinity in the field (Arish, Sinai, Egypt) and greenhouse hydroponic experiments at 100 mM NaCl concentration were conducted. Seven genotypes from Azerbaijan and Pakistan (IGs: 70782, 70430, 70764, 117703, 6057, 8447, and 70249) were identified as potential sources for high salinity tolerance.

Acces journal
Assessing the effect of a series of mutations on the dynamic behavior of phosphite dehydrogenase using molecular docking, molecular dynamics and quantum mechanics/molecular mechanics simulations

In this study, we combine molecular docking, molecular dynamics (MD) simulation, and Quantum Mechanics/Molecular Mechanics (QM/MM) to identify the impact of 30 mutations on the activity and stability of PTDH.

Acces journal
Monte Carlo Method and GA-MLR-Based QSAR Modeling of NS5A Inhibitors against the Hepatitis C Virus

In this study we identified new potential compounds for possible medical use against HCV using the quantitative structure–activity relationship (QSAR). A set of 36 NS5A inhibitors was used to build QSAR models using genetic algorithm multiple linear regression (GA-MLR) and Monte Carlo optimization and were implemented in the software CORAL.The constructed GA-MLR model with satisfactory statistical parameters (R2 = 0.915 and Q2 = 0.941) confirmed the predicted inhibitory activity for the compounds.

Acces journal
PltRNAdb: Plant transfer RNA database

In this paper, 8,768,261 scaffolds/chromosomes containing 229,093 giga-base pairs representing whole-genome sequences of 256 plant species were analyzed to identify tRNA genes. As a result, 331,242 nuclear, 3,216 chloroplast, and 1,467 mitochondrial tRNA genes were identified

Acces journal
Host Cell Proteases Mediating SARS-CoV-2 Entry: An Overview

In this review, we focus on the biochemical properties of host cell proteases that facilitate the entry of SARS-CoV-2, and we highlighted therapeutic small molecule candidates that have been proposed through in silico research.

Acces journal
Hybrid Molecules as Potential Drugs for the Treatment of HIV: Design and Applications

This review focuses on the recent development of hybrid compounds targeting integrase (IN), reverse transcriptase (RT), and protease (PR) proteins and provides a brief description of their chemical structures, structure-activity relationship, and binding mode. View Full-Text

Acces journal
Genome-wide analysis identified candidate variants and genes associated with heat stress adaptation in Egyptian sheep breeds

Sheep breeds from three locations in Egypt (Saidi, Wahati, and Barki) were studied with a total of 206 ewes. The heat tolerance index of the animals was calculated to identify animals with high and low heat tolerance based on their response to meteorological and physiological parameters. In this paper, we investigate the genomic structure that might control the adaptability of local sheep breeds to environmental stress under hot and dry conditions.

ABOUT THE LAB

A CENTRAL LAB TURNING HUMAN RESOURCES INTO ASSETS

Mohammed VI Polytechnic University (UM6P) is an international higher education institution established to put research and innovation at the service of education and development for Morocco and the African continent. The African Genome Center (AGC) aims to promote research and education in genomics, proteomics and bioinformatics in agriculture, environment, human health and food. The Bioinformatics Laboratory conducts research in bioinformatics, computational biology, and computational chemistry. The lab also provides bioinformatics consulting and data management services to AGC, UM6P researchers and their collaborators. Our laboratory addresses bioinformatics needs at the national and African levels. The African Genome Center has state-of-the-art NGS sequencers and mass spectrometry. In addition, UM6P recently acquired the largest high-performance computing (HPC) cluster in Africa. We aim to leverage these resources to centralize the bioinformatics needs internally and at the African level, and to develop innovative research and training programs.


Meet Our Team

Achraf El Allali

Assistant Professor



Rachid Elfermi

Research Assistant



Soukayna BAAMMI

PhD Candidate



Alsamman M Alsamman

Postdoctoral Fellow



Morad M. Mokthar

Postdoctoral Fellow



Wissal Liman

PhD Candidate



Samah Nassir

PhD. Student



Paola Corbetta

PhD Candidate




Get in Touch

  •      

  • Achraf.elallali@um6p.ma
  •              

  • Lot 660, Hay Moulay Rachid, Ben Guerir 43150